Clinical Study
GnRH Agonist versus hCG Trigger in Ovulation Induction with Intrauterine Insemination: A Randomized Controlled Trial
Table 1
Demographic characteristics of the patient population and intervention outcomes between two groups.
| | Variables | GnRHa-triggered cycles () | hCG-triggered cycles () | Total |
| | Mean age (years) | | | | | Infertility duration (years) | | | | | BMI (kg/m2) | | | | | Infertility type | | | | | Primary | 65.3% | 68.7% | 67.0% | | Secondary | 34.7% | 31.3% | 33.0% | | Infertility causes | | | | | Male factor | 80.6% | 82.8% | 81.7% | | Polycystic ovary syndrome | 34.7% | 33.3% | 34.0% | | Decreased ovarian reserve | 18.4% | 10.1% | 14.2% | | Tubal factor | 5.1% | 5.1% | 5.1% | | Adenomyosis | 4.1% | 5.1% | 4.6% | | Basal hormonal level | | | | | FSH (IU/L) | | | | | LH (IU/L) | | | | | AMH (ng/mL) | | | | | Ovulation rate | | | value | | Spontaneous cycles | 87.3% | 91.4% | 0.441 | | hMG stimulation | 81.5% | 83.3% | 0.600 | | Total | 85.7% | 89.9% | 0.392 | | Pregnancy rate | | | | | Biochemical pregnancy rate | | | | | Spontaneous cycles | 14.1% | 29.6% | 0.031 | | hMG stimulation | 14.8% | 22.2% | 0.694 | | Total | 14.3% | 28.3% | 0.023 | | Clinical pregnancy rate | | | | | Spontaneous cycles | 14.1% | 24.7% | 0.110 | | hMG stimulation | 11.1% | 16.7% | 0.670 | | Total | 13.3% | 23.2% | 0.096 |
|
|
GnRHa: gonadotropin receptor hormone agonist; hCG: human chorionic gonadotropin; BMI: body mass index; FSH: follicle-stimulating hormone; LH: luteinizing hormone; AMH: anti-Mullerian hormone; hMG: human menopausal gonadotropins.
|
