Research Article
PDE5A Suppresses Proteasome Activity Leading to Insulin Resistance in C2C12 Myotubes
Figure 5
Effects of PDE5 inhibitor icariin (Ica) on proteasome activity in PDE5A-overexpressed C2C12 myotubes. (a) Representative western blots showing the effects of icariin on the GFPu protein levels; (b) quantification of the GFPu protein levels in (a); (c) effects of icariin on the chymotrypsin-like activity of proteasome. . vs. the control group; , vs. the PDE5A-overexpression (OE) group.
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