Analysis of Regulatory T Cell Subsets and Their Expression of Helios and PD-1 in Patients with Hashimoto Thyroiditis

Table 1

Clinical and demographic features of the participants.

	HC	eHT	sHT	oHT	HT
Number	20	20	12	10	42
Sex (F/M)	15/5	19/1	9/3	9/1	37/5
Age (years)	38.85 ± 8.07	41.4 ± 13.55	40.9 ± 11.89	37.2 ± 14.59	40.29 ± 13.15
FT3 (pmol/L)	4.48 (4.28 -5.01)	4.35 (3.94 - 4.68)	4.42 (4.18 - 5.1)	3.34 (2.52 - 4.26)	4.21 (3.7 - 4.72)
FT4 (pmol/L)	15.5; (14.27-16.65)	15.28; (13.97-18.01)	14.92; (13.5-16.35)	9.67; (5.11-10.86)	14.46; (12.15-16.54)
TSH (mIU/L)	2.25 (1.82-2.84)	2.11 (1.59-3.42)	5.82 (4.68-6.7)	36.9 (23.68->100)	4.45 (2.11-11.02)
TPOAb (IU/ml)	13.0; (6.5 -22.75)	173.2; (69.97 -235.77)	248.45; (172.88-562.6)	473.5; (306.25- >600)	238.55; (160.9 -479.45)
TgAb (IU/ml)	32.21; (20.25 -51.08)	534.35; (310.15 -623.48)	402.05; (146.78-549.7)	1053.3; (797.1 -1835)	545.75; (345.78 -886.7)

Data was expressed as mean±SD or median (25th-75th percentile) on the basis of the distribution. HC: healthy controls; HT: Hashimoto thyroiditis; eHT: euthyroidism; sHT: subclinical hypothyroidism; oHT: clinical hypothyroidism; F: female; M: male; FT3: free triiodothyronine; FT4: free thyroxine; TSH: thyroid stimulating hormone; TPOAb: antithyroid peroxidase antibodies; TgAb: antithyroglobulin antibodies.
P < 0.05, comparison with health controls.
P < 0.05, comparison with eHT group.
P < 0.05, comparison with sHT group.