Research Article
IRF7 Gene Variations Confer Susceptibility to Autoimmune Thyroid Diseases and Graves’ Ophthalmopathy
Table 1
Clinical data of all subjects.
| | AITD | GD | HT | Control |
| | 889 | 592 | 297 | 770 | | Gender | — | — | — | — | | Male | 220 (24.75%) | 179 (30.24%) | 41 (13.80%) | 266 (34.55%) | | Female | 669 (75.25%) | 413 (69.76%) | 256 (86.20%) | 504 (65.45%) | | Age () | 36.29 ± 14.31 | 36.95 ± 14.70 | 34.96 ± 13.42 | 39.04 ± 8.79 | | Family history | — | — | — | — | | (+) | 181 (20.36%) | 120 (20.27%) | 61 (20.54%) | — | | (-) | 708 (79.64%) | 472 (79.73%) | 236 (79.46%) | | | Ophthalmopathy | | | | | | (+) | 111 (12.49%) | 106 (17.91%) | 5 (1.68%) | — | | (-) | 778 (87.51%) | 486 (82.09%) | 292 (98.32%) | — | | Onset of age | | | | — | | ≤18 years | 122 (13.72%) | 83 (14.02%) | 39 (13.13%) | — | | ≥19 years | 767 (86.28%) | 509 (85.98%) | 258 (86.87%) | — |
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AITD, autoimmune thyroid disease; GD, Graves’ disease; HT, Hashimoto’s thyroiditis.
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