Ginsenoside Rg1 Ameliorates Palmitic Acid-Induced Hepatic Steatosis and Inflammation in HepG2 Cells via the AMPK/NF-B Pathway

Figure 2

Inhibitory effect of G-Rg1 on PA-induced lipid accumulation in HepG2 cells. HepG2 cells were treated with 0.25 mM PA for 24 h and then cultivated with 40 or 80 μg/mL G-Rg1 for 6 h. The lipid accumulation was shown by Oil Red O staining (original magnification × 200) and the absorbance of the samples at 450 nm was measured using a microplate reader. (a) Effect of G-Rg1 on the intracellular triglyceride (TG) content in PA-treated HepG2 cells. (b) The data are expressed as the means ± SDs; n=3; P<0.05, P<0.001 (in comparison to the PA-treated model group).

(a)

(b)