Research Article

Metabolic Effects of Testosterone Hormone Therapy in Normal and Orchiectomized Male Rats: From Indirect Calorimetry to Lipolytic Enzymes

Table 2

Mean ± SD of indirect calorimetry parameters of all studied groups (n = 8/group).

ParametersShamT-ShamOrchT-Orch

VO2 (ml/h/kg)1182 ± 611509 ± 1131397 ± 611699 ± 94
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VO2 (ml/h/rat)456 ± 23598 ± 44441 ± 19566 ± 31
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b

VCO2 (ml/h/kg)999 ± 501364 ± 1161264 ± 601535 ± 55
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b

VCO2 (ml/h/rat)385 ± 19541 ± 46399 ± 19511 ± 18
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b

RQ0.84 ± 0.010.90 ± 0.010.91 ± 0.060.91 ± 0.01
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b

TEE (kcal/h/kg)5.93 ± 0.187.62 ± 0.766.90 ± 0.108.11 ± 0.01
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b

TEE (kcal/h/rat)2.10 ± 0.352.28 ± 0.232.07 ± 0.032.44 ± 0.01
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b

Food intake (g/rat)38.79 ± 9.5939.25 ± 3.6512.98 ± 3.3541.15 ± 14.91
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Body weight (g)385.50 ± 26.80396.45 ± 43.10315.83 ± 47.43332.83 ± 49.49
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b

Sham = normal control; T-Sham = normal rats treated with IM testosterone undecanoate preparation (100 mg/kg); Orch = orchiectomized rats; T-Orch = orchiectomized rats treated with IM testosterone undecanoate preparation (100 mg/kg); VO2 = volume of consumed oxygen; VCO2 = volume of the produced carbon dioxide; RQ = respiratory quotient (VCO2/VO2); TEE = total energy expenditure. Significant versus Sham group. Significant versus Orch group.