Increased Circulating Chemerin in Relation to Chronic Microvascular Complications in Patients with Type 2 Diabetes
Table 6
Characteristics of the subjects with and without diabetic peripheral neuropathy.
Without DPN
With DPN
p
Number (n)
131
100
Age (years)
53.91 (12.21)
55.80(11.25)
NS
Sex (male/female)
90/41
57/43
NS
Duration of diabetes (years)△
2(0.8,9)
8.0(3.25,12.0)
<0.001
Waist circumference(cm)
86.63 (11.12)
87.34(9.87)
NS
BMI (kg/m2)
24.91(3.46)
25.14(2.84)
NS
SBP (mmHg)
125.01(13.26)
126.00(11.45)
NS
DBP (mmHg)
78.37(7.47)
79.09(6.37)
NS
Glycated hemoglobin (%)
8.03(1.45)
8.60(1.73)
0.007
Triglycerides (mmol/l) △
1.62(1.15,2.21)
1.54(1.21,2.24)
NS
Total cholesterol (mmol/l)
4.62(1.03)
4.69(1.06)
NS
HDL cholesterol (mmol/l)△
1.07(0.30)
1.13(0.46)
NS
LDL cholesterol (mmol/l)
2.77(0.75)
2.69(0.88)
NS
Scr (umol/l)
55.53(13.58)
52.36(14.37)
NS
UAE (mg/24h)△
13.2(9,17.0)
12.6(10.35,15.6)
NS
hs-CRP (mg/L) △
3.6(1.2,6.6)
3.8(1.1,6.5)
NS
Chemerin (ng/ml)
97.69(40.27)
100.83(26.00)
NS
Medication
Oral hypoglycemic agents
33(25.1%)
25(25.0%)
NS
Insulin
98(74.9%)
75(75.3%)
NS
Hypertension (%)
71(54.19%)
42(42.0%)
NS
Numerical variables are expressed as the mean with SD and median (interquartile range). Categorical variables were presented as number (percentage). P-value for difference between the groups was calculated from the analysis of Student’s t test. BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; Scr, serum creatinine; UAE, urinary albumin excretion; hs-CRP, high sensitivity C-reactive protein; NS, not significant. UAE, urinary albumin excretion; △Natural logarithmic transformation was used in analysis.
