A Novel Pentapeptide Inhibitor Reduces Amyloid Deposit Formation by Direct Interaction with hIAPP

Figure 6

Inhibition of hIAPP cytotoxicity in INS-1 cells by adding FLPNF or NFGAIL. The cell viability was measured by the MTS assay. “Control” means INS-1 cells incubated in medium alone. The concentration of hIAPP added was 10 μM, while the concentrations of FLPNF and NFGAIL were 100 μM (the OD values read at 490 nm were presented as ; each experiment was repeated thrice; unpaired -test, ; ).