Clinical Characteristics and Management of Functional Pancreatic Neuroendocrine Neoplasms: A Single Institution 20-Year Experience with 286 Patients

Table 1

Summary of the reported cases of functional pancreatic neuroendocrine tumors.

	Gender (male/female)	Age	Duration	Size						Grade				Number		Heredity
				Single			Multiple
				≤1 cm	1-2  cm	≥2 cm	≤1 cm	1-2  cm	≥2 cm	NET-G1	NET-G2	NET-G3	Unknown	Single	Mutiple	Sporadic	MEN1
Total	103/183	45.55 ± 15.23	3.67 ± 4.28 (y)	25	179	64	5	9	4	120	157	9		268	18	277	9
Insulinoma	95/171	45.55 ± 15.25	3.86 ± 4.34 (y)	22	178	50	4	9	3	113	145	8		250	16	257	9
Glucagonoma	4/6	51.2 ± 13.58	1.54 ± 2.35 (y)	3		7				3	7			10	0	10	0
Somatostatinoma	1/2	48.33 ± 16.94	0.77 ± 0.33 (y)		1	1			1	3				2	1	3	0
ACTH-producing tumor	2/1	27.67 ± 8.5	8.67 ± 13.28 (m)			2	1				2	1		2	1	3	0
Gastrinoma	0/2	46 ± 7	1.02 ± 0.98 (y)			2				1	1			2	0	2	0
VIPoma	1/1	38.5 ± 3.5	1 (y)			2					2			2	0	2	0