GLP-1/GLP-1R Signaling Regulates Ovarian PCOS-Associated Granulosa Cells Proliferation and Antiapoptosis by Modification of Forkhead Box Protein O1 Phosphorylation Sites

Figure 2

Ovarian histopathology changed in PCOS model mice with or without treatment of liraglutide. H&E staining of thin sections of ovaries from mice of three groups, PCOS + liraglutide (c, f), PCOS (b, e), and vehicle (a, d). Micrographs were taken at magnifications: ×40, ×100, and scale bars represent 500 μm and 200 μm, respectively. The numbers of cystic follicles (g) and corpora lutea (h) were counted based on the images after staining. The data were expressed as mean ± SEM (N = 10/group). , , and .

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)