Rare Somatic MEN1 Gene Pathogenic Variant in a Patient Affected by Atypical Parathyroid Adenoma

Table 1

Clinical features of the three subjects reported in the literature with MEN1 syndrome and AA.

	Sex	Age	Ca^a	PTH^b	Parathyroid	Nephrolythiasis	MEN1 mutation	Other MEN1-related tumors	Others	Ref.
ID1	M	50	3.22 nmol/L	215 pmol/L	2 × 2.9 cm, 14 g	Bilateral	c.253A>T	Acromegalia, pituitary and adrenal, lipomas	CKD	Christakis et al. [18]
ID2	F	32	12 mg/dL	NA	0.7 cm	No	NA	Pancreas and thymus	No	Pal et al. [20]
ID3	F	44	14 mg/dL	1347 pg/mL	2 cm	Bilateral	c.912+1G>A	No	No	Present work

^aNormal range: 1.12–1.32 mmol/L or 8.4–10.2 mg/dL; ^bnormal range 15–65 pg/mL; CKD = chronic kidney disease.