Radiological Staging of Thyroid-Associated Ophthalmopathy: Comparison of T1 Mapping with Conventional MRI

<div>Methods for measurements of T1RT<sub>HS</sub>, T1RT<sub>CS</sub>, and SIR: coronal T1 mapping (a) and coronal fat-suppressed T2-weighted imaging (b) in a 52-year-old male with active TAO. Two circular regions of interest measuring 5–10 mm<sup>2</sup> were placed in the area with the highest (white) and lowest (black) signal intensity by naked eye, representing T1RT<sub>HS</sub> and T1RT<sub>CS</sub>, respectively (a). Meanwhile, two similar-sized regions of interest were manually placed in the area of the most inflamed EOM with the highest signal intensity as well as ipsilateral temporal muscle (b). T1RT<sub>HS</sub>, T1RT<sub>CS</sub>, and SIR values of the left/right eye were 2426/2006 ms, 1365/1422 ms, and 4.14/3.95, respectively. T1RT = T1 relaxation time; HS = hot spot; CS = cold spot; SIR = signal intensity ratio; TAO = thyroid-associated ophthalmopathy.</div>

International Journal of Endocrinology

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Figure 1

Figure 1: Radiological Staging of Thyroid-Associated Ophthalmopathy: Comparison of T1 Mapping with Conventional MRI 