Predictive Model of Type 2 Diabetes Remission after Metabolic Surgery in Chinese Patients
Table 2
Univariate analysis of remission predictors 1-2 years after surgery.
Remission group (N = 53)
Nonremission group (N = 34)
value
Age (yr)
<0.001
<40
22 (91.67%)
2 (8.33%)
≥40
31 (49.21%)
32 (50.79%)
Gender
0.101
Female
13 (48.15%)
14 (51.85%)
Male
40 (66.67%)
20 (33.33%)
Duration (yr)
0.011
≤5
32 (74.42%)
11 (25.58%)
>5
21 (47.73%)
23 (52.27%)
Surgical procedures
<0.001
Sleeve gastrectomy
23 (92.00%)
2 (8.00%)
Gastric bypass
30 (48.39%)
32 (51.62%)
BMI (kg/m2)
<0.001
<27.5
12 (41.38%)
17 (58.62%)
27.5–32.5
20 (55.56%)
16 (44.44%)
≥32.5
21 (95.45%)
1 (4.55%)
TG (mmol/L)
0.493
≥1.7
32 (58.18%)
23 (41.82%)
<1.7
21 (65.63%)
11 (34.37%)
CHOL (mmol/L)
0.426
≥4.14
40 (63.49%)
23 (36.51%)
<4.14
13 (54.17%)
11 (45.83%)
LDL (mmol/L)
0.534
≥2.59
26 (57.78%)
19 (42.22%)
<2.59
27 (64.29%)
15 (35.71%)
HDL (mmol/L)
0.279
>1.29
11 (73.33%)
4 (26.67%)
≤1.29
42 (58.33%)
30 (41.67%)
FPG (mmol/L)
0.099
<7.0
25 (71.43%)
10 (28.57%)
≥7.0
28 (53.85%)
24 (46.15%)
HbA1c (%)
0.270
<6.5
13 (76.47%)
4 (25.53%)
6.5 ≤ HbA1c < 9
27 (60.00%)
18 (40.00%)
≥9
13 (52.00%)
12 (48.00%)
FCP (ng/mL)
(N = 53)
(N = 34)
0.011
≤2.63
21 (47.73%)
23 (52.27%)
>2.63
32 (74.42%)
11 (25.58%)
ΔC30 (ng/mL)
(N = 49)
(N = 33)
0.499
<1.01
23 (56.10%)
18 (43.90%)
≥1.01
26 (63.41%)
15 (36.59%)
ΔC120 (ng/mL)
(N = 53)
(N = 34)
0.035
≤3.08
22 (50.00%)
22 (50.00%)
>3.08
31 (72.09%)
12 (27.91%)
ΔC30/ΔG30 (μg/mmol)
(N = 49)
(N = 33)
0.499
≤0.27
23 (56.10%)
18 (43.90%)
>0.27
26 (63.41%)
15 (36.59%)
ΔC120/ΔG120 (μg/mmol)
(N = 53)
(N = 34)
0.095
≤0.42
23 (52.27%)
21 (47.73%)
>0.42
30 (69.77%)
13 (30.22%)
HOMA-β (CP, DM) (%)
(N = 53)
(N = 34)
0.003
≤52.71
20 (45.45%)
24 (54.55%)
>52.71
33 (76.74%)
10 (23.26%)
HOMA-IR (CP)
(N = 53)
(N = 34)
0.011
≤2.08
21 (47.73%)
23 (52.27%)
>2.08
32 (74.42%)
11 (25.58%)
C-peptide AUC (ng/ml)
(N = 49)
(N = 33)
<0.001
≤30.93
16 (39.02%)
25 (60.98%)
>30.93
33 (80.49%)
8 (19.51%)
UmAlb(mg/L)
(N = 42)
(N = 32)
0.687
<20
15 (60.00%)
10 (40.00%)
≥20
27 (55.10%)
22 (44.90%)
Preoperative insulin use
<0.001
Yes
20 (43.48%)
26 (56.52%)
No
33 (80.49%)
8 (19.52%)
∗P < 0.05; indexes of islet function ((FCP, ΔC30, ΔC120, ΔC30/ΔG30, ΔC120/ΔG120, HOMA-β (CP, DM), HOMA-IR (CP), and C-peptide AUC) were grouped by median.
