Research Article

Effect of Denosumab on Bone Mineral Density of Hematopoietic Stem Cell Transplantation Recipients

Table 1

Baseline clinical characteristics of the study population (n = 33).

Age (years)52.6 ± 9.8
BMI (kg/m2)21.4 ± 3.6
CTx (ng/mL)0.62 ± 0.10
Serum calcium (mg/dL)9.1 ± 0.7
Serum phosphorous (mg/dL)3.4 ± 0.5
25-Hydroxyvitamin D (ng/mL)30.3 ± 10.0
Type of malignancy, n (%)
 Acute myeloid leukemia11 (33.3)
 Acute lymphoid leukemia14 (42.4)
 Myelodysplastic syndrome8 (24.3)
Baseline BMD (g/cm2)
 Lumbar spine0.923 ± 0.143
 Femur neck0.723 ± 0.093
 Total hip0.728 ± 0.105
Steroid exposure, n (%)22 (66.7%)

Continuous variables are presented as mean ± standard variation; categorical variables are presented as number (percentage); CTx, cross-linked C-terminal telopeptide of type 1 collagen; BMD, bone mineral density. Serum calcium level is adjusted calcium for albumin.