Association of rs944289, rs965513, and rs1443434 in TITF1/TITF2 with Risks of Papillary Thyroid Carcinoma and with Nodular Goiter in Northern Chinese Han Populations

Table 4

Association between rs965513 polymorphism and PTC/NG.

Genotype/allele	PTC vs. NC			NG vs. NC
	OR (95% CI)		AIC	OR (95% CI)		AIC
Codominant
G/G	1.00	0.008	2362.4	1.00	0.009	1795.4
G/A	1.25 (0.99–1.59)			0.82 (0.60–1.10)
A/A	3.81 (1.25–11.63)			4.38 (1.36–14.11)
Dominant
G/G	1.00	0.021	2364.7	1.00	0.500	1802.4
G/A + A/A	1.32 (1.04–1.67)			0.91 (0.68–1.21)
Recessive
G/G + G/A	1.00	0.013	2363.9	1.00	0.006	1795.2
A/A	3.64 (1.19–11.10)			4.53 (1.41–14.59)
Overdominant
G/G + A/A	1.00	0.083	2367.1	1.00	0.140	1800.6
G/A	1.23 (0.97–1.57)			0.80 (0.59–1.08)
Allele
G	1.00	0.007	—	1.00	0.932	—
A	1.34 (1.08–1.67)			1.01 (0.78–1.32)

Adjusted by age. PTC, papillary thyroid carcinoma; NG, nodular goiter; NC, normal control.