Association of rs944289, rs965513, and rs1443434 in TITF1/TITF2 with Risks of Papillary Thyroid Carcinoma and with Nodular Goiter in Northern Chinese Han Populations
Table 7
Association between rs944289 polymorphism and PTC by gender.
Genotype/allele
Female
Male
OR (95% CI)
AIC
OR (95% CI)
AIC
Codominant
C/C
1.00
0.005
1822.2
1.00
0.660
592.8
C/T
1.22 (0.95–1.57)
1.22 (0.80–1.86)
T/T
1.67 (1.22–2.28)
1.09 (0.62–1.92)
Dominant
C/C
1.00
0.014
1824.7
1.00
0.410
591.0
C/T + T/T
1.34 (1.06–1.69)
1.18 (0.79–1.76)
Recessive
C/C + C/T
1.00
0.005
1822.8
1.00
0.930
591.6
T/T
1.48 (1.12–1.94)
0.98 (0.59–1.63)
Overdominant
C/C + T/T
1.00
0.970
1830.7
1.00
0.390
590.9
C/T
1.00 (0.81–1.25)
1.18 (0.81–1.73)
Allele
C
1.00
0.001
—
1.00
0.600
—
T
1.29 (1.10–1.50)
1.08 (0.82–1.42)
Bonferroni correction was performed, and was defined as statistical significance. Significant values after Bonferroni correction in bold.
