Diagnostic Accuracy of the Triglyceride and Glucose Index for Insulin Resistance: A Systematic Review

Table 1

Study characteristics according to the reference standard of IR.

Reference	Design	Country	Population	Age	TyG, n	Ref. Study, n
Hyperinsulinemic-euglycemic clamp					6422	678
Guerrerro-Romero, [10]	Cross sectional	Mexico	Nondiabetic and diabetic adults	39.9 ± 9.3	99	99
Vasques, [11]	Cross sectional	Brasil	Nondiabetic and diabetic adults	47.3 ± 14.6	82	82
Bastard, [4]	Cohort study	France	Overweight postmenopausal women	57.3 ± 0.4	163	163
Guerrerro-Romero, [12]	Cross sectional	Mexico	Nondiabetic young adults	19.2 ± 1.4	5538	75
Qu, [13]	Cross sectional	China	Mixed population	Control 27 ± 4, 59 ± 10, PCOS 28 ± 6, IGT 59 ± 10, T2DM 58 ± 9	483	202
Almeda-Valdés, [5]	Cross sectional	Mexico	Nondiabetic adults	32.9 ± 11	57	57
HOMA-IR					63,500	63,500
Simental-Mendía, [7]	Cross sectional	Mexico	Nondiabetic adults	41.4 ± 11.2	748	748
Du, [14]	Cross sectional	China	Nondiabetic adults	50.6 (39.3–60.7)M, 51 (40.3–60.6)F	7629	7629
Lee, [15]	Cross sectional	Korea	Nondiabetic adults	42.4 ± 0.3M, 44.1 ± 0.3F	17029	17029
Er, [16]	Cross sectional	Taiwan	Nondiabetic adults	43 (38.1–50)M, 46 (40–51.2)F	511	511
Guerrero-Romero, [12]	Cross sectional	Mexico	Nondiabetic adults	19.2 ± 1.4	5538	5538
Mazidi, [17]	Cross sectional	China	General population	47.6	18318	18318
Thota, [18]	Cross sectional	Australia	Nondiabetic elderly adults	77.78 ± 7.16	486	486
Lim, [19]	Cross sectional	Korea	Nondiabetic adults	45.2 ± 15.0M, 44.3 ± 14.6F	11149	11149
Dorota-Łojko, [20]	Cross sectional	Poland	Nondiabetic and diabetic adults with bipolar disorder	58.1 ± 11.7	88	88
Other surrogates					2004	2004
Salazar, [21]	Cross sectional	Venezuela	Nondiabetic adults	39.6 ± 15.3	2004	2004

Median ± SD or median values. Healthy controls, polycystic ovarian syndrome, type 2 diabetes mellitus, and obese women. M: male; F: female; PCOS: polycystic ovarian syndrome; IGT: impaired glucose tolerance; T2DM: type 2 diabetes mellitus.