Diagnostic Accuracy of the Triglyceride and Glucose Index for Insulin Resistance: A Systematic Review

Table 2

Summary of the reference test.

Study	Reference test	IR definition	IR cutoff value
Guerrero-Romero, [10]	HIEC	M rate (insulin 40 μU/min/m^2)	2.8 insulin 40 mg/min/kg
Junqueira-Vasques, [11]	HC	NR	NR
Bastard, [4]	HIEC	M rate (insulin 75 μU/min/m^2)	11.56 mg/min/kgFFM
Guerrero-Romero, [12]	HIEC	M rate (insulin 40 μU/min/m^2)	2.8 insulin mg/min/kg
Qu, [13]	HIEC	M rate (insulin 1 mU/kg/min)	6.28 mg/min/kg
Almeda-Valdés, [5]	HIEC	M rate (insulin 50 mU/min/m^2)	6.39 mg/min/kgFFM
Simental-Mendía, [7]	HOMA-IR	Previous literature	≥2.8
Du, [14]	HOMA-IR	>75th percentile	3.5
Lee, [15]	HOMA-IR	>75th percentile	2.52
Er, [16]	HOMA-IR	>75th percentile	2.43
Guerrero-Romero, [12]	HOMA-IR	Not specified	≥2.9
Mazidi, [17]	HOMA-IR	Not specified	≥2.5
Thota, [18]	HOMA-IR	Not specified	NR
Lim, [19]	HOMA-IR	>75th percentile	NR
Dorota-Łojko, [20]	HOMA-IR	Previous literature	≥2.0
Salazar, [21]	HOMA-2IR	≥2.0	≥2.0

IR: insulin resistance; HC: hyperglycemic clamp; HIEC: hyperinsulinemic-euglycemic clamp; FFM: free-fat mass; NR: not reported; M = male; F = female; PreF = premenopausal female; PF = postmenopausal female.