Diagnostic Accuracy of the Triglyceride and Glucose Index for Insulin Resistance: A Systematic Review

Table 3

Summary of the diagnostic accuracy measures reported for the TyG index.

Study	Reference	TyG cutoff	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	PLR	NLR	DOR	AUC
Guerrero-Romero, [10]	HIEC	4.68	96	85	NR	NR	6.4	0.05	136	0.85
Guerrero-Romero, [12]	HIEC	4.68M	67M	72M	38M	90M	2.4M	0.45M	5.2M	0.67M
		4.55F	68F	66F	44F	84F	2.04F	0.48F	4.1F	0.68F
Qu, [13]	HIEC	4.55	67	72	NR	NR	2.4	0.46	5.22	0.77
Almeda-Valdés, [5]	HIEC	4.43	85.7	32.5	29.2	87.5	1.2	0.45	2.88	0.59
Simental-Mendía, [7]	HOMA-IR	4.65	84	45	81	84	1.5	0.36	4.29	NR
Guerrero-Romero, [12]	HOMA-IR	4.68M	90.9	99.7	98.3	98.6	NR	0.09	3319.6	NR
		4.55F
Mazidi, [17]	HOMA-IR	4.78	75.9	71.9	NR	NR	2.7	0.34	8.05	0.81
Dorota-Łojko, [20]	HOMA-IR	4.69	73.8	75.6	NR	NR	3.0	0.35	8.72	0.78
Salazar, [21]	HOMA-2IR	4.49	82.6	82.1	NR	NR	4.6	0.21	21.77	0.88

M: male; F: female; HC: hyperglycemic clamp; HIEC: hyperinsulinemic-euglycemic clamp; TyG: triglyceride/glucose index; PPV: positive predictive value; NPV: negative predictive value; PLR: positive likelihood ratio; NLR: negative likelihood ratio; DOR: diagnostic odds ratio; AUC: area under the curve; NR: not reported.