Recovery of Prenatal Baicalein Exposure Perturbed Reproduction by Postnatal Exposure of Testosterone in Male Mice

Table 4

Administration of testosterone on the levels of serum testosterone (T), follicle stimulating hormone (FSH), and luteinizing hormone (LH) of adult male Wistar mice exposed to baicalein (BC) prenatally.

Hormone	Group	Control/BC-exposed groups	4.16 mg T/kg·BW (BC + T) (#)
Testosterone (ng/ml)	Control	7.38 ± 0.11	7.39 ± 0.15
	30 mg	7.14 ± 0.13 (−3.34),	7.34 ± 0.13 (−0.68),
	60 mg	6.54 ± 0.13 (−11.48),	7.25 ± 0.12 (−1.93),
	90 mg	5.61 ± 0.11 (−23.94),	7.02 ± 0.16 (−5.04),
		, F = 38.64	, F = 1.346
FSH (ng/ml)	Control	4.55 ± 0.11	4.57 ± 0.18
	30 mg	5.36 ± 0.15 (17.99),	4.71 ± 0.18 (3.17),
	60 mg	8.03 ± 0.18 (76.75),	5.54 ± 0.18 (21.33),
	90 mg	9.84 ± 0.33 (116.49),	5.87 ± 0.29 (28.39),
		, F = 109.5	, F = 0.8870
LH (ng/ml)	Control	1.59 ± 0.15	1.57 ± 0.158
	30 mg	1.62 ± 0.231 (1.98),	1.60 ± 0.22 (1.42),
	60 mg	2.12 ± 0.27 (33.40),	1.88 ± 0.25 (19.17),
	90 mg	2.86 ± 0.28 (79.79),	2.23 ± 0.26 (45.64),
		; F = 6.529	; F = 6.35

Values are mean ± SEM of six animals; # denotes n = 4. Values in the parentheses are percent changes from that of control. Significance was checked from control males to F1 BC exposed and BC exposed administered with T groups. Significance was considered at .