The Composition of Gut Microbiota in Patients Bearing Hashimoto’s Thyroiditis with Euthyroidism and Hypothyroidism

Table 1

The clinical characteristics of the participants.

	CON; (n = 34)	HTN; (n = 45)	HTH; (n = 18)	value
Age (years)	29.6 ± 0.6	34.6 ± 1.0	36.3 ± 2.1	0.0003
BMI (kg/m^2)	21.4 ± 0.6	22.2 ± 0.5	23.7 ± 0.9	0.0674
Course (months)	0	13.6 ± 2.7	29.7 ± 10.7	0.0001
Levothyroxine use (n, %)	0	13 (30%)	13 (72%)	0.0001
TT3 (ng/mL)	1.1 ± 0.02	1.01 ± 0.02	1.10 ± 0.05	0.0812
TT4 (µg/dL)	7.37 ± 0.24	7.15 ± 0.16	6.36 ± 0.26	0.0169
FT3 (pg/mL)	2.91 ± 0.06	2.94 ± 0.05	3.08 ± 0.07	0.2013
FT4 (ng/dL)	1.23 ± 0.03	1.26 ± 0.03	1.06 ± 0.05	0.0002
TSH (µIU/mL)	1.87 ± 0.16	2.19 ± 0.12	12.70 ± 4.66	0.0001
A-TG > 115U/mL (n/total)	0/31	41/43	11/14	<0.0001
A-TPO > 34 U/mL (n/total)	0/33	28/43	9/14	<0.0001

Data are shown as mean ± SEM or number (%). CON, healthy controls; HTN, patients bearing Hashimoto’s thyroiditis with euthyroidism; HTH, HT patients with hypothyroidism; BMI, body mass index; TT3, total triiodothyronine; TT4, total thyroxine; FT3, free triiodothyronine; FT4, free thyroxine; TSH, thyroid-stimulating hormone; A-TG, thyroglobulin antibody; A-TPO, thyroperoxidase antibody. ∗Significant difference compared to the CON group. # Significant difference compared with the HTN group.