Relationship between Serum Indirect Bilirubin Level and Insulin Sensitivity: Results from Two Independent Cohorts of Obese Patients with Impaired Glucose Regulation and Type 2 Diabetes Mellitus in China

Table 3

Correlations between serum bilirubin levels (TBIL, DBIL, and IBIL) and metabolism variables of the two subgroups in cohort 1.

	Control group						IGR/T2DM group
	TBIL (μmol/L)		DBIL (μmol/L)		IBIL (μmol/L)		TBIL (μmol/L)		DBIL (μmol/L)		IBIL (μmol/L)
	r	value	r	value	r	value	r	value	r	value	r	value
Weight (kg)	−0.215	0.229	−0.276	0.120	−0.042	0.816	−0.266	0.106	−0.207	0.213	−0.259	0.116
BMI (kg/m^2)	−0.195	0.276	−0.321	0.069	0.031	0.862	−0.294	0.073	−0.257	.0119	−0.293	0.074
FPG (mmol/L)	0.039	0.830	−0.003	0.986	−0.033	0.857	−0.030	0.860	−0.123	0.462	0.027	0.873
FINS (mU/L)	0.047	0.794	0.127	0.481	0.082	0.651	−0.317	0.052	−0.289	0.078	−0.352	0.030
FC-p (pmol/L)	−0.123	0.496	−0.028	0.877	−0.022	0.902	−0.330	0.043	−0.273	0.097	−0.349	0.032
M value (mg/kg·min)	0.078	0.666	0.249	0.163	−0.026	0.884	0.325	0.046	0.319	0.051	0.324	0.047
ALT (U/L)	0.237	0.184	0.356	0.042	0.123	0.497	0.285	0.083	0.323	0.048	0.254	0.124
AST (U/L)	0.235	0.189	0.268	0.131	0.145	0.420	0.211	0.204	0.194	0.243	0.200	0.228
ALP (U/L)	0.161	0.371	0.154	0.392	0.090	0.618	−0.001	0.994	0.012	0.943	0.018	0.915
GGT (U/L)	0.183	0.308	0.347	0.048	0.106	0.557	0.077	0.647	0.083	0.621	0.057	0.734
TC (mmol/L)	−0.126	0.484	−0.138	0.443	−0.070	0.698	0.011	0.950	−0.251	0.128	0.099	0.556
TG (mmol/L)	−0.100	0.578	−0.166	0.356	0.002	0.992	−0.285	0.083	−0.269	0.103	−0.278	0.091
HDL-c (mmol/L)	0.034	0.849	−0.116	0.521	−0.058	0.750	0.063	0.706	−0.080	0.634	0.147	0.379
LDL-c (mmol/L)	−0.017	0.927	−0.040	0.826	0.014	0.938	0.023	0.889	−0.123	0.463	0.031	0.855

IGR/T2DM, impaired glucose regulation and type 2 diabetes mellitus; BW, body weight; BMI, body mass index; FPG, fasting plasma glucose; FINS, fasting insulin; FC-p, fasting C-peptide; M value, glucose disposal rate (GDR); ALT, alanine transaminase; AST, aspartate aminotransferase; GGT, gamma-glutamyl transferase; TC, total cholesterol; TG, triglyceride; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; TBIL, total bilirubin; DBIL, direct bilirubin; IBIL, indirect bilirubin. Spearman r correlation, . Statistically significant values are indicated in bold.