Research Article

TIR-Domain-Containing Adaptor-Inducing Interferon-β (TRIF) Is Involved in Glucose Metabolism in Adipose Tissue through the Insulin/AKT Signaling Pathway

Figure 2

Effects of TRIF deficiency on the IPGTT and ITT. (a) At the age of 46 weeks, mice were fasted for 16 h and injected i.p. with 1.5 g glucose/kg bodyweight, and (b) blood glucose and insulin were measured before and after glucose injection at the indicated time points. (c) At the age of 47 weeks, mice were fasted for 4 h and injected i.p. with 0.75 U insulin/kg bodyweight for the ITT. Blood glucose levels were determined and are shown as percent changes from (d) basal blood glucose levels (, ) (n = 12/group).
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