Follicle-Stimulating Hormone Positively Associates with Metabolic Factors in Perimenopausal Women

Table 1

The characteristics of the study population.

	Premenopause	Perimenopause	value
	N = 154	N = 124
Age (ys)	46.27 ± 2.50	50.06 ± 5.17	<0.001
Weight (kg)	65.92 ± 10.20	66.41 ± 10.30	0.697
WC (cm)	86.92 ± 9.22	90.10 ± 9.40	0.006
BMI (kg/m^2)	25.86 ± 3.52	26.60 ± 3.77	0.095
SBP (mmHg)	130.49 ± 20.31	132.00 ± 20.78	0.544
DBP (mmHg)	78.56 ± 12.90	78.71 ± 10.86	0.919
FT3 (pmol/L)	4.71 ± 0.48	4.88 ± 1.15	0.114
FT4 (pmol/L)	15.49 ± 2.02	15.42 ± 3.50	0.842
TSH (mIU/L)	2.95 ± 1.67	2.72 ± 1.65	0.270
FSH (IU/L)	9.30 (6.45∼13.93)	20.87 (8.06∼54.87)	<0.001
LH (IU/L)	6.00 (4.10∼8.47)	16.64 (6.60∼32.32)	<0.001
E2 (pg/ml)	55.12(31.92∼98.29)	61.11(19.16∼146.80)	0.851
PRG (ng/ml)	0.52 (0.33∼1.74)	0.39 (0.20∼0.97)	0.003
FPG (mmol/L)	5.78 ± 1.49	5.81 ± 1.51	0.906
HbA1c (%)	5.75 ± 0.94	5.81 ± 0.79	0.604
TC (mmol/L)	4.78 ± 0.85	5.20 ± 0.95	<0.001
LDL-C (mmol/L)	2.73 (2.32∼3.08)	2.97 (2.48∼3.45)	0.001
HDL-C (mmol/L)	1.39 (1.20∼1.55)	1.36 (1.18∼1.62)	0.900
TG (mmol/L)	0.95 (0.78∼1.34)	1.07 (0.83∼1.71)	0.023
ALT (U/L)	13.85 ± 5.42	17.02 ± 6.56	<0.001
AST (U/L)	17.57 ± 4.86	19.77 ± 4.85	<0.001
Crea (μmol/L)	61.79 ± 6.16	62.71 ± 5.36	0.096
UA (μmol/L)	263.42 ± 59.82	291.12 ± 72.90	0.001

All data are expressed as mean ± standard deviation or median with interquartile range. Abbreviations: WC: waist circumference; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; FT3: free triiodothyronine; FT4: free thyroxine; TSH: thyroid stimulating hormone; FSH: follicle stimulating hormone; LH: luteinizing hormone; E2: estrogen; PRG: progesterone; FPG: fasting plasma glucose; TC: total cholesterol; LDL-C: low density lipoprotein cholesterol; HDL-C: high density lipoprotein cholesterol; TG: triglyceride; ALT: Alanine Aminotransferase; AST: Aspartate transaminase; Crea: creatine; UA: uric acid.