A Comparison of Two Operation Methods Revealed the Risk Factors and the Necessity of LN-prRLN Dissection in Papillary Thyroid Carcinoma: A Retrospective Cohort Study in FUSCC
Table 2
Demographic characteristics of patients enrolled in this study.
Variables
No. of patients (%)
value
Group A (N = 378)
Group B (N = 1109)
Age (y, mean ± SD)
43.12 ± 11.06
47.17 ± 11.36
≤0.001
Sex (Female/Male)
291 (77.0%)/87 (23.0%)
843 (76.0%)/266 (24.0%)
0.702
Multifocality (yes/No)
129 (34.1%)/249 (65.9%)
380 (34.27%)/729 (65.73%)
0.961
Size (mm, mean ± SD)
11.14 ± 7.78
9.23 ± 6.33
≤0.001
Extensive invasion (yes/No)
36 (9.5%)/342 (90.5%)
93 (8.39%)/1016 (91.61%)
0.497
Co-HT (yes/No)
140 (37.0%)/238 (63.0%)
227 (20.47%)/882 (79.53%)
≤0.001
Conodular goiter (yes/No)
58 (15.3%)/320 (84.7%)
219 (19.75%)/890 (80.25%)
0.058
cN1a (Yes/No)
96 (25.4%)/282 (74.6%)
332 (30.0%)/777 (70.0%)
0.100
LNM
cLNMa (yes/No)
210 (55.6%)/168 (44.4%)
464 (41.84%)/645 (58.16%)
≤0.001
cLNMa size (mm, mean ± SD)
7.86 ± 5.31
—
Positive cLNMa no. (p50, (min-max))
1 (0–29)
0 (0–17)
≤0.001
Dissected cLNMa no. (p50, (min-max))
5 (0–33)
4 (0–25)
≤0.001
LLNM (yes/No)
88 (23.3%)/290 (76.7%)
52 (4.69%)/1057 (95.31%)
≤0.001
Positive LLNM no. (p50, (min-max))
5 (1–37)
3 (1–33)
0.022
Dissected LLNM no. (p50, (min-max))
27 (2–75)
24.5 (3–75)
0.089
LN-prRLN metastasis (yes/No)
129 (34.1%)/249 (65.9%)
—
—
Size of LN-prRLN(mm, mean ± SD)
5.82 ± 3.60
—
—
Recurrence (%)
6 (1.59%)
29 (2.61%)
0.255
Follow-up (months, mean ± SD)
23.19 ± 16.09
42.02 ± 21.12
≤0.001
SD: standard deviation; Co-HT: concurrent Hashimoto’s thyroiditis; Conodular goiter: concomitant with nodular goiter; cN1a: clinical positive central lymph nodes metastasis; cLNMa:central lymph nodes anterior to the right recurrent laryngeal nerve; LNM: Lymph node metastasis; cLNM: Central lymph node metastasis; LLNM: Lateral lymph node metastasis. After the Shapiro-Wilk test and homogeneity of variance test, we found that the data did not conform to a normal distribution and that the variance was not uniform. Therefore, we used the Wilcoxon test to calculate the difference between the two groups.
