Clinical Study

Parathyroid Hormone Reduction Predicts Transient Hypocalcemia after Total Thyroidectomy: A Single-Center Prospective Study

Table 1

Demographic, clinical, and biochemical characteristics of the 176 patients with papillary thyroid carcinoma undergoing radical operation.

CharacteristicValue

Gender (male/female)39/137
Age (year, median, range)46.00 (17–73)
Tumor diameter (cm, median, range)1.00 (0.20–5.00)
Duration of illness (day, median, range)60 (1–2920)
Node number (single/multi/NA)46/125/5
Total thyroidectomy (radical operation)
 Bilateral CLND108
 Ipsilateral CLND13
 Bilateral CLND + bilateral cervical LND12
 Bilateral CLND + ipsilateral cervical LND35
 Ipsilateral CLND + ipsilateral cervical LND8
Pathology
 Pathologic N (N0/N1/N2/N3)65/111/0/0
 Pathologic T (T1/T2/T3/T4/)132/16/28/0
 Pathology stage (I/II/III/IV)147/22/4/3
Preoperative serum PTH (pg/ml, median, range)46.00 (16.52–234.9)
Preoperative serum Ca (mmol/l, median, range)2.35 (2.04–3.21)
POD1 serum PTH (pg/ml, median, range)18.00 (1.20–70.20)
POD1 serum Ca (mmol/l, median, range)2.00 (1.56–2.48)
Postoperative complications
 Convulsion57
 Numbness29
 None90
Hypocalcemia (male/female)
 POD1 (n = 176)4/51
 POD3 (n = 101)8/51
 POD5 (n = 71)4/23
 POD7 (n = 60)2/11
 POD30 (n = 100)1/4
 POD90 (n = 74)0/4
 POD180 (n = 57)0/2
 POD365 (n = 35)0/1

POD1/3/5/7/30/90/180/365, postoperative day 1, 3, 5, 7, 30, 90, 180, and 365. CLND, central lymph node dissection; LND, lymph node dissection.