Clinical Study
Parathyroid Hormone Reduction Predicts Transient Hypocalcemia after Total Thyroidectomy: A Single-Center Prospective Study
Table 4
The risk factors for the transient hypocalcemia on postoperative day 1.
| Variable | Univariate | Multivariate | β | OR (95% CI) | | β | OR (95% CI) | |
| The whole cohort (n = 176) | | | | | | | Gender | 1.268 | 3.555 (1.302–9.703) | 0.013 | 1.160 | 3.189 (0.924–11.007) | 0.067 | Age (year) | −0.017 | 0.983 (0.954–1.012) | 0.251 | −0.001 | 0.999 (0.961–1.039) | 0.957 | PTH reduction (%) | 0.047 | 1.048 (1.028–1.068) | <0.001 | 0.043 | 1.044 (1.023–1.065) | <0.001 | Preoperative PTH (pg/ml) | 0.002 | 1.002 (0.958–1.019) | 0.849 | −0.010 | 0.990 (0.969–1.011) | 0.337 | Preoperative serum Ca (mmol/L) | −1.671 | 0.188 (0.015–2.295) | 0.190 | −3.023 | 0.049 (0.001–1.786) | 0.100 | Tumor diameter (cm) | 0.410 | 1.507 (1.059–2.145) | 0.023 | 0.447 | 1.564 (0.981–2.496) | 0.060 | Surgery | 0.952 | 2.590 (0.725–9.261) | 0.143 | 1.002 | 2.722 (0.518–14.318) | 0.237 |
| Bilateral group (n = 125) | | | | | | | Gender | 1.235 | 3.440 (1.243–9.523) | 0.017 | 1.155 | 3.176 (0.907–11.113) | 0.071 | Age (year) | −0.015 | 0.985 (0.955–1.015) | 0.320 | 0.003 | 1.003 (0.964–1.044) | 0.883 | PTH reduction (%) | 0.047 | 1.048 (1.028–1.069) | <0.001 | 0.042 | 1.043 (1.022–1.064) | <0.001 | Preoperative PTH (pg/ml) | −0.005 | 0.995 (0.977–1.013) | 0.562 | −0.018 | 0.982 (0.960–1.004) | 0.114 | Preoperative serum Ca (mmol/L) | −1.123 | 0.325 (0.029–3.595) | 0.360 | −0.3024 | 0.049 (0.001–1.920) | 0.107 | Tumor diameter (cm) | 0.389 | 1.476 (1.032–2.111) | 0.033 | 0.465 | 1.592 (0.992–2.554) | 0.054 |
| Female patients (n = 137) | | | | | | | Age (year) | −0.016 | 0.984 (0.953–1.016) | 0.316 | −0.001 | 0.999 (0.958–1.042) | 0.964 | PTH reduction (%) | 0.051 | 1.053 (1.030–1.076) | <0.001 | 0.049 | 1.050 (1.026–1.075) | <0.001 | Preoperative PTH (pg/ml) | 0.004 | 1.004 (0.987–1.022) | 0.643 | −0.006 | 0.994 (0.972–1.016) | 0.582 | Preoperative serum Ca (mmol/L) | −1.784 | 0.168 (0.012–2.278) | 0.180 | −3.569 | 0.028 (0.001–1.366) | 0.071 | Tumor diameter (cm) | 0.446 | 1.563 (1.070–2.283) | 0.021 | 0.499 | 1.647 (1.003–2.704) | 0.049 |
| Male patients (n = 39) | | | | | | | Age (year) | −0.024 | 0.976 (0.900–1.059) | 0.558 | −0.012 | 0.988 (0.869–1.123) | 0.853 | PTH reduction (%) | 0.027 | 1.028 (0.988–1.069) | 0.171 | 0.023 | 1.023 (0.981–1.068) | 0.285 | Preoperative PTH (pg/ml) | −0.028 | 0.973 (0.909–1.041) | 0.424 | −0.051 | 0.951 (0.867–1.043) | 0.284 | Preoperative serum Ca (mmol/L) | 0.104 | 1.019 (0.000–31.581) | 0.984 | −0.280 | 0.756 (0.000–12.050) | 0.964 | Tumor diameter (cm) | 0.120 | 1.127 (0.364–3.489) | 0.836 | 0.194 | 1.215 (0.242–6.100) | 0.813 |
|
|