Research Article

Diabetes and Risk of Post-Fragility Hip Fracture Outcomes in Elderly Patients

Table 1

Comparison of general characteristics of the two groups of patients.

Nondiabetic (N = 483)Diabetic (N = 161) value

Demographics
 Age (years)78.0 ± 8.677.3 ± 7.60.310
 Gender (n (%))0.066
 Male170 (35.2)44 (27.4)
 Female313 (64.8)117 (72.7)
Substance use (n (%))
 Smoking habit81 (16.8)13 (8.1)0.007
 Alcohol misuse51 (10.6)17 (10.6)1.000
Laboratory test
 Haemoglobin (g/l)113.0 ± 19.2114.0 ± 20.40.568
 Serum albumin (g/l)36.8 ± 4.637.6 ± 4.00.035
 eGFR (ml min−1·1.73 m−2)75.4 ± 21.170.6 ± 24.30.027
BMD at the neck of the femur (g/cm3)0.55 ± 0.220.59 ± 0.220.193
BMD at the spine (g/cm3)0.50 ± 0.350.54 ± 0.370.255
Charlson comorbidity index (n (%))0.891
 0–2441 (91.3)145 (90.1)
 3-439 (8.1)15 (9.3)
 5–63 (0.6)1 (0.6)
 Mean0.7 ± 1.00.9 ± 1.20.051
Comorbidity (n (%))
 Hypertension195 (40.4)114 (70.8)<0.001
 Coronary artery disease69 (14.3)37 (23.0)0.010
 Cardiac failure29 (6.0)10 (6.2)0.924
 Cerebrovascular accidents68 (14.1)29 (18.0)0.227
 Kidney disease23 (4.8)18 (11.2)0.004
 Respiratory disease63 (13.0)19 (11.8)0.682
 Gastrointestinal diseases32 (6.6)5 (3.1)0.176
 Cancer27 (5.6)9 (5.6)1.000
Previous fracture (n (%))55 (11.4)18 (11.2)0.943
Preinjury activity (n (%))0.348
 Grade I380 (90.7)134 (91.8)
 Grade II31 (7.4)9 (6.2)
 Grade III8 (1.9)2 (1.4)
 Grade IV0 (0)1 (0.7)
Fracture type (n (%))0.689
 Femoral neck282 (58.6)92 (57.1)
 Trochanteric193 (40.0)65 (40.4)
 Subtrochanteric7 (1.4)4 (2.5)
Time awaiting surgery (days)5.0 (4.0–8.0)6.0 (5.0–8.0)0.031
Therapeutic regimen (n (%))0.47
 No surgery106 (21.9)31 (19.3)
 Underwent surgery377 (78.1)130 (80.7)
Surgical treatment (n (%))0.238
 Internal fixation76 (20.2)34 (26.2)
 Hemiarthroplasty153 (40.6)54 (41.5)
 Total hip replacement148 (39.3)42 (32.3)
Antiosteoporosis medication (n (%))
 Prescribed after hip fracture146 (34.8)50 (34.2)0.896
 Continuous users in the 12 months80 (19.1)25 (17.1)0.598

Data are represented as mean (SD), median (IQR), or n (%). eGFR, estimated glomerular filtration rate; BMD, bone mineral density.