Vitamin D Auto-/Paracrine System Is Involved in Modulation of Glucocorticoid-Induced Changes in Angiogenesis/Bone Remodeling Coupling

Table 2

Cortical bone strength of rat femurs after prednisolone and vitamin D₃ administration, M ± m (n = 7).

Groups	Control	Prednisolone administration	Prednisolone and vitamin D3 administration
Maximal load at failure (N)	99.9 ± 5.6	80.2 ± 2.3^∗	89.5 ± 2.8^#
Stiffness (N/mm)	355.4 ± 10.9	267.2 ± 10.5^∗	262.8 ± 7.9
Toughness (mJ)	58.3 ± 0.8	43.7 ± 1.2^∗	62.1 ± 1.4^#

Maximal load at failure, stiffness, and toughness were analyzed by three-point bending. Values are given as means ± SEM. vs. control; vs. prednisolone administration.