Risk Factors Related to New-Onset Diabetes after Renal Transplantation in Patients of a High Complexity University Hospital in Colombia, 20 Years of Experience
Table 3
Bivariable and multivariable analyses for risk factors associated with NODAT in patients with renal transplantation between 1995 and 2014.
Characteristics
Bivariable
Multivariable
OR (95% CI)
value
OR (95% CI)
value
Age >50 years
2.9 (1.8–4.7)
<0.0001
3.18 (1.6–6.3)
0.001
Male gender
1.27 (0.8–2.0)
0.312
—
—
Afro-descendant ethnicity
1.6 (0.87–2.9)
0.129
2.74 (1.1–6.5)
0.023
BMI >30 kg/m2
4.2 (1.7–10.0)
0.001
3.6 (1.3–9.7)
0.010
Family history of DM
2.15 (1.3–3.6)
0.003
1.7 (0.9–3.3)
0.098
Pretransplant fasting plasma glucose >100 mg/dl
3.82 (2.0–7.0)
<0.0001
2.9 (1.4–6.4)
0.005
Serum triglycerides >200 mg/dl
2.3 (1.4–3.6)
<0.0001
2.5 (1.4–4.4)
0.002
Pretransplant hepatitis C antibody test
0.4 (0.09–2.0)
0.302
—
—
Steroid treatment
3.7 (0.94–14.0)
0.060
3.8 (0.32–46)
0.286
Treatment with tacrolimus
0.69 (0.38–1.26)
0.236
—
—
Treatment with mTOR inhibitor
2.02 (1.0–3.8)
0.034
1.5 (0.55–4.1)
0.417
CMV infection
1.89 (1.01–3.5)
0.047
1.85 (0.7–4.9)
0.203
Prophylaxis for CMV
0.96 (0.49–1.8)
0.917
—
—
Retransplant
0.65 (0.29–1.43)
0.287
—
—
NODAT : new-onset diabetes after transplantation; BMI : body mass index; DM : diabetes mellitus; CMV: cytomegalovirus; OR: odds ratio; CI: confidence interval.
