Vitamins Modulate the Expression of Antioxidant Genes in Progesterone-Treated Pancreatic β Cells: Perspectives for Gestational Diabetes Management

Figure 3

Relative expression of progesterone-regulated genes in RINm5F cells. Cells were incubated, for 6 or 24 h, with 0.1, 1.0, or 100 μM progesterone. Data are presented as means ± SEM of three experiments in duplicates. (a) Scd1; (b) Duox1; (c) GPx6; (d) Hmox1; (e) Hspa1a; (f) Prdx4. S/C: expression in the progesterone-treated cultures in comparison to control. indicates difference compared to control. indicates difference between the time points, for the same progesterone concentration (ρ < 0.05). PG: progesterone.

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