Vitamins Modulate the Expression of Antioxidant Genes in Progesterone-Treated Pancreatic β Cells: Perspectives for Gestational Diabetes Management

Table 1

Regulated genes in progesterone-treated RINm5F cells evaluated by PCR array.

Gene	6 h			24 h
	Progesterone concentrations
	0.1 μM	1 μM	100 μM		0.1 μM	1 μM	100 μM
Cyba	2.17	1.50	−1.46		2.69	2.33	1.27
Dhcr24	−1.55	−1.45	−5.77		−1.36	−2.13	−1.72
Dnm2	−1.51	−1.56	−5.46		−1.48	−2.04	−2.10
Duox1	2.45	1.59	1.45		4.54	2.84	-1.04
Ercc6	−1.11	−1.38	−3.61		−1.20	−1.48	−2.14
Fancc	−1.27	−1.53	−3.31		−1.34	−2.04	−2.86
Fmo2	1.15	−2.01	−1.76		5.55	5.89	1.96
Gpx2	−1.13	−1.17	−2.39		1.15	−1.11	−2.33
Gpx6	1.57	2.82	−1.15		4.06	4.82	1.12
Gpx7	1.03	−1.83	−2.35		3.07	2.53	2.87
Hmox1	−1.09	−1.57	2.66		−1.26	−1.63	4.18
Hspa1a	3.81	4.85	7.98		7.14	3.80	1.24
Idh1	1.05	−1.03	−2.56		1.28	1.34	−2.20
Lpo	−2.81	1.20	−1.33		1.90	3.62	23.08
Ncf1	−1.03	−1.16	−3.81		−1.19	−1.33	−3.68
Ncf2	−1.60	1.04	−14.08		1.53	−4.72	1.95
Ngb	−1.51	−1.56	−4.64		1.76	2.29	−1.28
Noxa1	−2.37	−1.22	−7.60		−1.26	−1.90	−2.15
Noxo1	1.17	−1.71	−7.83		−1.36	1.09	−2.47
Nqo1	−1.28	−1.70	−9.26		−1.22	−1.82	3.18
Prnp	−1.56	−2.23	−2.10		−1.46	−2.01	−2.70
Ptgs1	−1.33	−1.71	−2.15		−1.55	−2.05	−1.96
Idh1	3.73	4.60	2.09		1.10	1.35	3.08
Idh1	−1.11	1.39	−1.42		2.00	2.15	1.38
Slc38a1	2.20	4.75	−1.66		1.92	2.96	−2.90
Srxn1	−1.11	−1.13	−3.61		−1.09	−1.23	4.63
Txnip	−1.16	−1.56	−50.94		−2.19	−3.53	−26.65
Ucp2	−1.62	−1.79	−4.51		−1.40	−1.73	−2.10
Vim	1.58	1.01	−7.99		1.29	2.55	−1.14