Research Article

Serum Levels and Placental Expression of NGAL in Gestational Diabetes Mellitus

Table 1

Clinical characteristics of normal pregnant controls and women with GDM.

GDM (n = 49)Control (n = 39) value

Age (years)32.47 ± 4.6831.77 ± 4.960.497
Gestational age (week)39.14 ± 0.6239.00 ± 0.460.275
Parity1 (1, 1)1 (0, 1)0.346
Prepregnancy BMI (kg/m2)23.15 ± 3.0622.69 ± 3.000.488
Current BMI (kg/m2)28.57 ± 2.9629.19 ± 3.860.402
FPG1 (mmol/L)5.00 ± 0.474.47 ± 0.34<0.01
1 hPG (mmol/L)10.07 ± 1.387.16 ± 1.39<0.01
2 hPG (mmol/L)8.04 ± 1.326.34 ± 0.89<0.01
FPG2 (mmol/L)4.92 ± 0.614.50 ± 0.40<0.01
FINS (μU/mL)12.81 ± 4.6210.72 ± 3.460.023
HOMA-IR2.80 ± 1.112.15 ± 0.730.003
TC (mmol/L)5.87 ± 0.996.28 ± 0.970.058
TG (mmol/L)3.30 ± 1.362.63 ± 0.750.006
HDL-C (mmol/L)1.76 ± 0.301.89 ± 0.270.041
LDL-C (mmol/L)3.38 ± 0.733.61 ± 0.660.136
VLDL-C (mmol/L)0.74 ± 0.270.78 ± 0.280.558
Birth weight (g)3598.89 ± 430.053448.72 ± 366.970.092

Annotation: BMI: body mass index; FPG1: fasting plasma glucose in the second trimester; 1 hPG: 1 h plasma glucose after glucose loading; 2 hPG: 2 h plasma glucose after glucose loading; FPG2: fasting plasma glucose in the third trimester; FINS: fasting insulin level; HOMA-IR: HOMA-insulin resistance index; TC: total cholesterol; TG: triglycerol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; VLDL-C: very low-density lipoprotein cholesterol. Data are mean ± SD and medians (25–75%); values statistically evaluated as insignificant and significant.