Research Article

Serum Kisspeptin and Its Relation to Metabolic Parameters and Glucose Metabolism in Prepubertal and Pubertal Obese Children

Table 2

Correlations between serum kisspeptin and other parameters.

Parametersβ-Coefficient95% confidence interval value

Age−1.058−3.131 to 1.0140.316
Female−2.520−11.656 to 6.6160.588
Tanner stages
 II-III18.3702.127 to 34.6130.027
 IV-V6.810−9.057 to 22.6780.399

BMI SDS−2.584−8.024 to 2.8560.350
Waist circumference percentile0.057−0.094 to 0.2080.457
Body fat percentage SDS−0.248−5.689 to 5.1940.928
C-peptide2.707−3.415 to 8.8300.384
HbA1c14.6406.853 to 22.427<0.001
Fasting plasma glucose4.459−4.232 to 13.1510.313
AUC glucose0.551−1.017 to 2.1200.489
AUC insulin−0.002−0.005 to 0.0020.366
WBISI0.944−1.175 to 3.0620.381
QUICKI57.837−68.757 to 184.4320.369
HOMA-IR−0.139−1.561 to 1.2820.847
IGI−1.662−4.368 to 1.0450.228
HOMA-β0.001−0.006 to 0.0070.824
Total cholesterol−0.310−5.973 to 5.3530.914
HDL-C−17.925−35.953 to 0.1030.051
LDL-C−1.834−7.942 to 4.2750.555
Triglyceride6.505−0.380 to 13.3900.064

AUC, area under the curve; BMI, body mass index; HbA1c, glycated hemoglobin; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; HOMA-β, HOMA index; IGI, insulinogenic index; LDL-C, low-density lipoprotein cholesterol; QUICKI, quantitative insulin sensitivity check index; SDS, standard deviation score; WBISI, whole-body insulin sensitivity index. Correlations were evaluated using median regression analysis.