Serum Kisspeptin and Its Relation to Metabolic Parameters and Glucose Metabolism in Prepubertal and Pubertal Obese Children
Table 2
Correlations between serum kisspeptin and other parameters.
Parameters
β-Coefficient
95% confidence interval
value
Age
−1.058
−3.131 to 1.014
0.316
Female
−2.520
−11.656 to 6.616
0.588
Tanner stages
II-III
18.370
2.127 to 34.613
0.027
IV-V
6.810
−9.057 to 22.678
0.399
BMI SDS
−2.584
−8.024 to 2.856
0.350
Waist circumference percentile
0.057
−0.094 to 0.208
0.457
Body fat percentage SDS
−0.248
−5.689 to 5.194
0.928
C-peptide
2.707
−3.415 to 8.830
0.384
HbA1c
14.640
6.853 to 22.427
<0.001
Fasting plasma glucose
4.459
−4.232 to 13.151
0.313
AUC glucose
0.551
−1.017 to 2.120
0.489
AUC insulin
−0.002
−0.005 to 0.002
0.366
WBISI
0.944
−1.175 to 3.062
0.381
QUICKI
57.837
−68.757 to 184.432
0.369
HOMA-IR
−0.139
−1.561 to 1.282
0.847
IGI
−1.662
−4.368 to 1.045
0.228
HOMA-β
0.001
−0.006 to 0.007
0.824
Total cholesterol
−0.310
−5.973 to 5.353
0.914
HDL-C
−17.925
−35.953 to 0.103
0.051
LDL-C
−1.834
−7.942 to 4.275
0.555
Triglyceride
6.505
−0.380 to 13.390
0.064
AUC, area under the curve; BMI, body mass index; HbA1c, glycated hemoglobin; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; HOMA-β, HOMA index; IGI, insulinogenic index; LDL-C, low-density lipoprotein cholesterol; QUICKI, quantitative insulin sensitivity check index; SDS, standard deviation score; WBISI, whole-body insulin sensitivity index. Correlations were evaluated using median regression analysis.