The Impact of Preconception TSH on the Reproductive Outcomes of Infertile Women Undergoing the First Fresh D3 Embryo Transfer Cycle
Table 1
The general characteristics of the included women based on TSH levels.
Low-TSH (0.27–2.5mIU/L)
High-normal TSH (2.5–4.2mIU/L)
N
1008
778
Age (years)
31.82 (4.75)
31.62 (4.59)
0.371
BMI (kg/m2)
23.71 (3.27)
23.98 (3.38)
0.088
AMH (pmol/L)
25.62 (21.03)
27.17 (23.65)
0.143
FT4 (pmol/L)
16.77 (6.81)
16.51 (5.56)
0.385
FT3 (pmol/L)
4.78 (0.72)
4.83 (0.73)
0.156
FSH (IU/L)
7.52 (2.32)
7.67 (2.3)
0.169
Endometrial thickness (mm)
11.29 (2.31)
11.46 (2.37)
0.138
Duration of infertility (year)
3.52 (2.68)
3.68 (2.78)
0.212
Insemination methods of transferred embryos
ICSI
246 (24.4%)
214 (27.5%)
0.172
IVF
752 (74.6%)
552 (71%)
IVF/ICSI
10 (1%)
12 (1.5%)
Ovarian stimulation protocol
GnRH agonist
915 (90.8%)
720 (92.5%)
0.355
GnRH antagonist
88 (8.7%)
56 (7.2%)
Mild ovarian stimulationa
5 (0.5%)
2 (0.3%)
Causes of infertility
Male factors (azoospermatism)b
171 (17%)
159 (20.4%)
0.107
Male factors (others)
56 (5.6%)
46 (5.9%)
Female mixed factors
38 (3.8%)
42 (5.4%)
Ovulation failure
70 (6.9%)
53 (6.8%)
Pelvic and fallopian tube factors
345 (34.2%)
259 (33.3%)
Factors on both sides
257 (25.5%)
160 (20.6%)
Unexplained
71 (7%)
59 (7.6%)
Type of infertility
Primary
545 (54.1%)
392 (50.4%)
0.126
Secondary
463 (45.9%)
386 (69.6%)
Number of transferred embryos
1
110 (10.9%)
80 (10.3%)
0.669
2
898 (89.1%)
698 (89.7%)
Number of high-quality transferred embryos
0
150 (14.9%)
137 (17.6%)
0.298
1
258 (25.6%)
193 (24.8%)
2
600 (59.5%)
448 (57.6%)
athe couples with mild ovarian stimulation were of poor ovarian response. Generally, those couples would have the embryos vitrified for subsequent frozen-thawed transfer cycle; b the couples with infertile cause of male factor (azoospermatism) were provided with donor sperm for insemination.
