Serum Levels of Asprosin, a Novel Adipokine, Are Significantly Lowered in Patients with Acromegaly
Table 3
Bivariate correlation analysis of serum asprosin levels.
Variables
Acromegaly
Controls
Total
r
r
r
Gender
−0.428
<0.001
−0.565
<0.001
−0.323
<0.001
Age (y)
−0.285
0.018
−0.260
0.005
−0.226
0.002
SBP (mm Hg)
0.069
0.576
−0.095
0.315
−0.36
0.630
DBP (mm Hg)
0.098
0.431
−0.034
0.717
0.019
0.802
BMI (kg/cm2)
0.077
0.538
0.344
<0.001
0.270
<0.001
ALT (U/L)
−0.186
0.131
−0.028
0.769
−0.032
0.666
AST (U/L)
−0.038
0.808
−0.099
0.306
−0.029
0.725
Cr (μmol/l)
−0.415
0.001
−0.049
0.604
−0.001
0.991
UA (μmol/l)
−0.172
0.186
−0.351
<0.001
−0.270
<0.001
TC (mmol/l)
0.614
<0.001
0.003
0.978
0.184
0.025
TG (mmol/l)
0.292
0.084
0.028
0.769
0.069
0.403
HDL-C (mmol/l)
0.198
0.247
0.315
0.001
0.333
<0.001
LDL-C (mmol/l)
0.560
<0.001
−0.130
0.182
0.088
0.294
FBG (mmol/l)
−0.220
0.075
0.072
0.448
−0.091
0.223
2h-Glu (mmol/l)
−0.053
0.672
0.106
0.397
−0.022
0.807
Glu-AUC (mmol/l)
−0.147
0.237
—
—
—
—
D-max (mm)
0.015
0.910
—
—
—
—
Course (y)
−0.273
0.026
—
—
—
—
IGF-1 SDS
−0.295
0.016
—
—
—
—
GH (ng/ml)
−0.215
0.083
—
—
—
—
GH-Nadir (ng/ml)
−0.249
0.046
—
—
—
—
GH-AUC (ng/ml)
−0.285
0.021
—
—
—
—
SBP: systolic blood pressure; DBP: diastolic blood pressure; FBG: fasting blood glucose; 2 h-Glu: 2-hour postprandial blood glucose; GLU-AUC: glucose of area under curve of 75 g OGTT test; D-max: maximum of tumor diameter; Course: course of acromegaly; IGF-1 SDS: SDS of insulin-like growth factor; GH-Nadir: nadir GH level after 75 g OGTT; GH-AUC: growth hormone of the area under curve after 75 g OGTT; NA, not available. Bold values indicate statistical significance .
