Postoperative Nomogram for Predicting Cancer-Specific and Overall Survival among Patients with Medullary Thyroid Cancer
Table 1
Baseline demographic and clinical characteristics of MTC patients who underwent total thyroidectomy and neck lymph nodes dissection.
Variables
Training cohort (%) (n = 867)
Test cohort (%) (n = 370)
Age (y)
<48
299 (34.5)
137 (37.0)
48–71
468 (54.0)
184 (49.7)
>71
100 (11.5)
49 (13.3)
Race
Black
67 (7.7)
28 (7.6)
White
740 (85.4)
319 (86.2)
Others
60 (6.9)
23 (6.2)
Sex
Male
388 (44.8)
141 (38.1)
Female
479 (55.2)
229 (61.9)
Number of nodules
Solitary
589 (67.9)
260 (70.3)
Multiple
278 (32.1)
110 (29.7)
Tumor size(mm)
<20
381 (43.9)
162 (43.8)
20–40
318 (36.7)
151 (40.8)
>40
168 (19.4)
57 (15.4)
T
T1a
168 (19.4)
83 (22.4)
T1b
175 (20.2)
77 (20.8)
T2
204 (23.5)
92 (24.9)
T3a
118 (13.6)
48 (13.0)
T3b
125 (14.4)
42 (11.4)
T4a
52 (6.0)
17 (4.6)
T4b
25 (2.9)
11 (3.0)
N
N0
391 (45.1)
200 (54.1)
N1a
169 (19.5)
48 (13.0)
N1b
307 (35.4)
122 (33.0)
M
M0
810 (93.4)
354 (95.7)
M1
57 (6.6)
16 (4.3)
Number of removal LNs
1–3
158 (18.2)
70 (18.9)
≥4
709 (81.8)
300 (81.1)
Total LNs
0–11
367 (42.3)
178 (48.1)
12–32
253 (29.2)
89 (24.1)
33–90
247 (28.5)
103 (27.8)
PLNs
0
393 (45.3)
200 (54.1)
1–16
378 (43.6)
130 (35.1)
17–73
96 (11.1)
40 (10.8)
LNR
<19.0%
514 (59.3)
250 (67.6)
19.0%–49.0%
191 (22.0)
60 (16.2)
>49.0%
162 (18.7)
60 (16.2)
Number of removal LNs, number of removal lymph nodes; total LNs, the number of regional lymph nodes by pathological findings; pLNs, positive lymph nodes; LNR, lymph node ratio.
