The Phlorotannin-Rich Fraction of Ecklonia cava Extract Attenuated the Expressions of the Markers Related with Inflammation and Leptin Resistance in Adipose Tissue

Figure 2

Effects of E. cava extract on macrophages and T-cell infiltration in visceral fat of high-fat diet- (HFD-) induced obese mice. (a) CD11b as a marker of total macrophage; (b) CD80 as a marker of M1 macrophage; and (c) CD206 as a marker of M2 macrophage expression mRNA levels were measured by qRT-PCR in visceral fat of standard normal fat diet with 0.9% saline (NFD/saline; open bar), HFD with 0.9% saline (HFD/saline; black bar), HFD with E. cava extract (HFD/ECE; red bar), and HFD with Garcinia cambogia extract (HFD/GCE; blue bar) groups. (d, e) CD8a and CD4 as T-cell expression levels were determined by qRT-PCR in visceral fat of the same groups. All mRNA levels expressed relative level and normalized ß-actin of the NFD/saline group. The same letters represent no significant difference ().

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