A Missense Mutation in IRS1 is Associated with the Development of Early-Onset Type 2 Diabetes

Table 3

Information of candidate pathogenic gene loci.

CHR	POS	ID	REF	ALT	Gene	HGVSc	HGVSp
2	88890039		T	C	EIF2AK3	c.1087T > C	p.Ser363Pro
2	227661318	rs1043152329	G	A	IRS1	c.2137C > T	p.His713Tyr
10	101559103	rs149854486	C	T	ABCC2	c.1007C > T	p.Thr336Met
13	113765138		G	C	F7	c.265G > C	p.Glu89Gln
18	19757062		A	G	GATA6	c.1282A > G	p.Ile428Val

CHR: chromosome; POS: position; ID: identification; REF: reference; ALT: alternative; HGVSc: human genome variation society cDNA; HGVSp: human genome variation society protein.