Adrenal (Pro)renin Receptor Expression and Serum Soluble (Pro)renin Receptor Concentration in Primary Aldosteronism
Table 1
Clinical characteristics of pathologically confirmed aldosterone-producing adenoma group.
Characteristics
n
44
Age
50.7 ± 11.3
Gender (male/female)
23/21
Body mass index (kg/m2)
23.4 ± 4.1
Blood pressure (mmHg)
Systolic
140.5 ± 16.9
Diastolic
88.3 ± 11.8
Laboratory data
Creatinine (mg/dL)
0.77 ± 0.21
eGFR (mL/min/1.73 m2)
78.5 ± 19.0
Serum potassium (mEq/L)
3.1 ± 0.4
LDL-cholesterol (mg/dL)
118.0 ± 30.4
HDL-cholesterol (mg/dL)
58.7 ± 17.5
Triglyceride (mg/dL)
101 (72.3–155.8)
Plasma glucose (mg/dL)
96.5 (88.3–114.8)
Hemoglobin A1c (%)
5.5 (5.3–6.1)
HOMA-R
1.2 (0.8–1.9)
HOMA-β
50.1 (38.0–78.4)
Hormonal data
PAC (pg/mL)
387 (347.8–549.5)
PRA (ng/ml/h)
0.3 (0.2–0.5)
U-aldo (μg/day)
29 (20–38)
Adenoma size (mm2)
62.0 (43.9–85.9)
Lateralization ratio in AVS after cosyntropin loading
14.4 (7.5–22.0)
Contralateral suppression (yes/no)
(42/2)
PRA: plasma renin activity; PAC: plasma aldosterone concentration; U-aldo: urinary aldosterone excretion; and AVS: adrenal venous sampling. Data are expressed as mean ± SD or median (25th–75th).
