Adrenal (Pro)renin Receptor Expression and Serum Soluble (Pro)renin Receptor Concentration in Primary Aldosteronism

Table 3

Single correlation analyses with serum soluble (pro)renin receptor levels in the pathologically confirmed aldosterone-producing adenoma group.

	rs	value
Age	0.181	0.239
Body mass index (kg/m^2)	0.220	0.151
Blood pressure (mmHg)
Systolic	−0.092	0.551
Diastolic	0.009	0.954
Laboratory data
Creatinine (mg/dL)	0.385	0.009
eGFR (mL/min/1.73 m^2)	−0.368	0.014
LDL-cholesterol (mg/dL)	0.085	0.581
HDL-cholesterol (mg/dL)	−0.193	0.210
Triglyceride (mg/dL)	0.125	0.419
Serum potassium (mEq/L)	0.038	0.806
Plasma glucose (mg/dL)	0.382	0.011
Hemoglobin A1c (%)	0.420	0.005
HOMA-R	0.399	0.007
HOMA-β	−0.038	0.805
Hormonal data
PRA (ng/ml/h)	0.129	0.405
PAC (pg/mL)	−0.033	0.830
U-aldo (μg/day)	0.231	0.131
Immunohistochemical findings
CYP11B2	0.096	0.535
CYP11B2 multiplied by tumor area	−0.020	0.897
(P)RR	0.111	0.469
(P)RR multiplied by tumor area	0.039	0.800

eGFR: estimated glomerular filtration rate; LDL: low-density lipoprotein; HDL: high-density lipoprotein; HOMA-R: homeostasis model assessment for insulin resistance; HOMA-β: homeostasis model assessment of β-cell function; PRA: plasma renin activity; PAC: plasma aldosterone concentration; and U-aldo: urinary aldosterone excretion.