Research Article
Adrenal (Pro)renin Receptor Expression and Serum Soluble (Pro)renin Receptor Concentration in Primary Aldosteronism
Table 3
Single correlation analyses with serum soluble (pro)renin receptor levels in the pathologically confirmed aldosterone-producing adenoma group.
| | rs | value |
| Age | 0.181 | 0.239 | Body mass index (kg/m2) | 0.220 | 0.151 | Blood pressure (mmHg) | | | Systolic | −0.092 | 0.551 | Diastolic | 0.009 | 0.954 | Laboratory data | | | Creatinine (mg/dL) | 0.385 | 0.009 | eGFR (mL/min/1.73 m2) | −0.368 | 0.014 | LDL-cholesterol (mg/dL) | 0.085 | 0.581 | HDL-cholesterol (mg/dL) | −0.193 | 0.210 | Triglyceride (mg/dL) | 0.125 | 0.419 | Serum potassium (mEq/L) | 0.038 | 0.806 | Plasma glucose (mg/dL) | 0.382 | 0.011 | Hemoglobin A1c (%) | 0.420 | 0.005 | HOMA-R | 0.399 | 0.007 | HOMA-β | −0.038 | 0.805 | Hormonal data | | | PRA (ng/ml/h) | 0.129 | 0.405 | PAC (pg/mL) | −0.033 | 0.830 | U-aldo (μg/day) | 0.231 | 0.131 | Immunohistochemical findings | | | CYP11B2 | 0.096 | 0.535 | CYP11B2 multiplied by tumor area | −0.020 | 0.897 | (P)RR | 0.111 | 0.469 | (P)RR multiplied by tumor area | 0.039 | 0.800 |
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eGFR: estimated glomerular filtration rate; LDL: low-density lipoprotein; HDL: high-density lipoprotein; HOMA-R: homeostasis model assessment for insulin resistance; HOMA-β: homeostasis model assessment of β-cell function; PRA: plasma renin activity; PAC: plasma aldosterone concentration; and U-aldo: urinary aldosterone excretion.
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