Is There Room for SERMs or SARMs as Alternative Therapies for Adult Male Hypogonadism?

Table 1

Selective androgen receptor agonists (SARMs): ongoing clinical trials.

Status	Study title	Conditions	Interventions	Locations
Not yet recruiting	Multimodality Intervention for Function and Metabolism in SCI	(i) Spinal cord injuries	(i) Drug: SARM; (ii) Behavioral: hybrid exercise
Active, not recruiting	Study to Evaluate the Safety and Efficacy of 13 weeks of the Selective Androgen Receptor Modulator (SARM) GSK2881078 in Chronic Obstructive Pulmonary Disease (COPD)	(i) Cachexia	(i) Drug: GSK2881078; (ii) Placebo	USA
Active, not recruiting	Pembrolizumab and Enobosarm in Treating Patients With Androgen Receptor Positive Metastatic Triple Negative Breast Cancer	(i) Androgen receptor positive; (ii) Estrogen receptor negative; (iii) HER2/neu negative; (iv) And 3 more	(i) Drug: enobosarm; (ii) Pembrolizumab	USA
Recruiting	A Selective Androgen Receptor Modulator for Symptom Management in Prostate Cancer	(i) Prostate cancer	(i) Drug: LY2452473; (ii) Drug: placebo	USA

Data from https://clinicalltrials.gov.