Resistin Activates p65 Pathway and Reduces Glycogen Content through Keratin 8

Figure 5

Resistin-regulated accumulation of glycogen through K8 involves p65. HepG2 cells were treated with human recombinant resistin protein, and the protein level (a) and mRNA level (b) of p65 were determined by using Western blot and qRT-PCR, respectively. (c) HepG2 cells were treated with or without resistin after cotransfection with K8 siRNA and p65 expression plasmid, and the glycogen content determined. (d) HepG2 cells were treated with or without resistin after cotransfection with K8 siRNA and p65 siRNA, and the glycogen content was determined. Data are presented as mean ± SD. and .

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