Research Article

The Effect of Inflammation on the Formation of Thyroid Nodules

Table 1

Clinical characteristics of all subjects with and without TNs.

VariablesTNs (n = 986)Non-TNs (n = 1082)SMD

Age (years)47.23 (13.99)36.93 (11.32)<0.0010.809
Gender (female, n)467 (47.4)254 (23.5)<0.0010.516
Creatinine (mmol/L)75.10 (22.58)77.08 (17.38)<0.0010.098
Body mass index (kg/m2)24.04 (6.55)23.52 (2.84)0.0020.104
Systolic blood pressure (mmHg)122.87 (13.86)118.53 (12.16)<0.0010.333
Diastolic blood pressure (mmHg)79.45 (9.57)77.75 (9.94)<0.0010.174
Fasting blood sugar (mmol/L)5.56 (1.09)5.26 (1.02)<0.0010.277
Uric acid (mmol/L)392.35 (98.97)401.44 (97.05)0.0350.093
Triglyceride (mmol/L)1.38 (0.84)1.34 (1.05)<0.0010.036
Cholesterol (mmol/L)5.03 (0.89)4.78 (0.88)<0.0010.281
High-density lipoprotein (mmol/L)1.42 (0.33)1.39 (0.33)0.1130.070
Low-density lipoprotein (mmol/L)2.99 (0.76)2.79 (0.74)<0.0010.263
Thyroid stimulating hormone (mIU/L)1.79 (0.96)1.90 (0.90)0.0050.124
Free triiodothyronine (nmol/L)5.15 (0.58)5.20 (0.53)0.0310.095
Free thyroxine (nmol/L)15.76 (2.18)16.23 (2.20)<0.0010.215
White blood cell (109 cells/L)6.55 (1.72)6.34 (1.56)0.0030.131
Neutrophil (109 cells/L)3.64 (1.25)3.54 (1.19)0.0640.081
Lymphocyte (109 cells/L)2.32 (0.67)2.23 (0.58)0.0010.148
Monocyte (109 cells/L)0.40 (0.13)0.39 (0.12)0.0410.090
Neutrophil/lymphocyte ratio1.66 (0.73)1.67 (0.64)0.7670.005
Lymphocyte/monocyte ratio6.22 (2.27)6.10 (1.92)0.5140.057
Monocyte/high-density lipoprotein ratio0.30 (0.14)0.30 (0.13)0.5160.029

Data were presented as mean (SD) or number (%). TNs: thyroid nodules; SMD: standardized mean difference. ; .