Recurrent Germline Mutations of CHEK2 as a New Susceptibility Gene in Patients with Pheochromocytomas and Paragangliomas

Figure 2

The somatic CHEK2 mutations detected of three patients compared with the germline mutation sites. The other one patient’ sufficient FFPE sample was not obtained. The red arrows indicate the mutation sites, (a) for Patient 1, (b) for Patient 2, and (c) for Patient 3. “B” means the germline sites from peripheral blood leukocytes, and “T” means the somatic sites from FFPE tumor tissues.

(a)

(b)

(c)