Research Article

PIK3R1, SPNB2, and CRYAB as Potential Biomarkers for Patients with Diabetes and Developing Acute Myocardial Infarction

Figure 5

Validation of screened hub genes in mice MI model. The relative mRNA expression level of PIK3R1 (a), SPNB2 (b), and CRYAB (c) at 1d and 1w after MI using qPCR analysis. The protein expression levels of left ventricle at 1d and 1w after MI utilizing ELISA, including PIK3R1 (d), SPNB2 (e), and CRYAB (f). The expression levels of proteins, including PIK3R1 (g) and SPNB2 (h), were demonstrated to be negatively correlated to LVEF. The expression levels of protein CRYAB (i) were demonstrated to be positively correlated to LVEF. ; ns, not significant.
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