Research Article

Association between Lipid Profiles and Serum Urate: A Cross-Sectional Study in Southwestern China

Table 1

Characteristics of the subjects.

TotalAge (years) value
18–2930–3940–4950–5960–6970–99

Females
N55,7426,36612,40718,30611,1725,3342,157
Age (years)44 (36–52)27 (25–28)35 (32–37)44 (42–47)53 (51–56)63 (61–66)74 (71–77)<0.001
Body mass index (kg/m2)22.57 ± 3.0020.51 ± 2.5121.67 ± 2.7022.76 ± 2.7723.53 ± 2.9323.98 ± 3.0623.74 ± 3.21<0.001
Serum urate (μmol/L)281.61 ± 58.44283.35 ± 54.51275.42 ± 55.89272.48 ± 55.77290.21 ± 59.47296.24 ± 61.99308.72 ± 68.73<0.001
LDL-C (mmol/L)2.78 ± 0.742.39 ± 0.632.53 ± 0.652.78 ± 0.703.08 ± 0.743.15 ± 0.762.99 ± 0.81<0.001
HDL-C (mmol/L)1.51 ± 0.301.53 ± 0.291.50 ± 0.301.51 ± 0.301.51 ± 0.311.50 ± 0.321.53 ± 0.33<0.001
Total cholesterol (mmol/L)4.78 ± 0.864.30 ± 0.704.44 ± 0.734.76 ± 0.795.18 ± 0.835.29 ± 0.855.13 ± 0.90<0.001
Triglycerides (mmol/L)1.09 (0.80–1.53)0.82 (0.65–1.10)0.92 (0.71–1.26)1.09 (0.82–1.48)1.32 (0.98–1.81)1.42 (1.05–1.91)1.42 (1.07–1.85)<0.001
FPG (mmol/L)4.93 ± 0.514.68 ± 0.434.82 ± 0.454.91 ± 0.485.07 ± 0.535.19 ± 0.545.21 ± 0.58<0.001
Serum creatinine (μmol/L)55.00 (49.80–60.70)53.50 (48.80–58.80)53.80 (48.80–59.00)54.70 (49.50–60.30)56.20 (50.80–62.00)57.00 (51.40–63.40)59.80 (53.70–65.90)<0.001
eGFR (mL/min/1.73 m2)108.47 ± 13.31124.76 ± 7.96117.65 ± 8.18108.74 ± 8.50100.58 ± 8.6993.00 ± 8.3584.32 ± 8.09<0.001

Males
N66,6095,94214,25821,38513,9787,2533,793
Age (years)45 (37–54)27 (25–28)35 (32–37)44 (42–47)53 (51–56)63 (61–66)75 (72–79)<0.001
Body mass index (kg/m2)24.31 ± 2.9523.14 ± 3.2124.19 ± 3.0424.64 ± 2.8524.64 ± 2.7424.27 ± 2.8623.53 ± 2.95<0.001
Serum urate (μmol/L)385.79 ± 71.80398.85 ± 71.86395.95 ± 70.82387.31 ± 70.71381.23 ± 71.47368.43 ± 71.69368.64 ± 71.66<0.001
LDL-C (mmol/L)3.02 ± 0.742.78 ± 0.722.97 ± 0.723.09 ± 0.733.10 ± 0.753.04 ± 0.762.86 ± 0.79<0.001
HDL-C (mmol/L)1.29 ± 0.291.27 ± 0.271.26 ± 0.281.27 ± 0.281.29 ± 0.291.36 ± 0.311.40 ± 0.32<0.001
Total cholesterol (mmol/L)4.85 ± 0.834.49 ± 0.794.76 ± 0.804.93 ± 0.814.96 ± 0.834.92 ± 0.854.76 ± 0.89<0.001
Triglycerides (mmol/L)1.49(1.07–2.08)1.24(0.90–1.78)1.52(1.08–2.14)1.61(1.16–2.22)1.56(1.13–2.14)1.34(0.98–1.84)1.21(0.89–1.63)<0.001
FPG (mmol/L)4.97 ± 0.564.76 ± 0.484.85 ± 0.514.95 ± 0.555.06 ± 0.585.16 ± 0.595.22 ± 0.59<0.001
Serum creatinine (μmol/L)77.00 (70.20–84.20)77.20 (71.00–83.60)77.30 (70.70–84.00)76.90 (70.20–84.10)76.80 (69.90–84.30)76.60 (69.40–84.50)78.20 (71.00–85.20)<0.001
eGFR (mL/min/1.73 m2)101.48 ± 13.13116.30 ± 10.33109.76 ± 10.24102.70 ± 9.9496.15 ± 9.6389.88 ± 8.9982.03 ± 7.79<0.001

FPG: fasting plasma glucose; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; eGFR: estimated glomerular filtration rate.