Factors That Affect the Sensitivity of Imaging Modalities in Primary Hyperparathyroidism
Table 1
Clinical features and laboratory test results in PHPT patients.
Total patients
Number
352
Age, y
53.4 ± 12.5
Sex (female : male)
2.96 : 1
Duration of disease, y
1 (0.2–4.0)
Nephrolithiasis (n, %)
136 (38.64%)
Fracture (n, %)
30 (8.52%)
Serum calcium, mmol/L
2.76 ± 0.31
Serum phosphate, mmol/L
0.88 ± 0.20
Serum albumin, g/L
38.25 ± 3.72
Albumin-corrected serum calcium, mmol/L
2.79 ± 0.32
Serum PTH, pg/mL
247.3 (150.0–537.9)
Serum ALP, IU/L
93 (68–142)
Serum 25(OH)D, nmol/L
27.24 (18.05–38.68)
24 h urinary calcium, mmol/24 h
6.03 (4.35–8.09)
Serum creatinine, μmol/L
63 (54–79)
MDRD, ml/min/1.73 m2
99 (80–113)
BMD L1-L4, g/cm2
0.93 ± 0.20
T-score L1-L4
−1.58 ± 1.65
BMD femoral neck, g/cm2
0.76 ± 0.14
T-score femoral neck
−1.30 ± 1.16
Osteoporosis (T ≦ −2.5) (%)
36.27%
Negative imaging results (n, %)
18 (5.11%)
Tumor length (cm)
1.8 (1.3–2.7)
PTH: parathyroid hormone; ALP: alkaline phosphatase; 25(OH)D: 25-hydroxyvitamin D; MDRD: modification of diet in renal disease; BMD: bone mineral density.