Irisin as a Potential Biomarker Associated with Myocardial Injuries in Patients with Severe Hypothyroidism

Table 1

Baseline characteristics of control and severe hypothyroidism groups.

	Control group (n = 17)	Severe hypothyroidism group (n = 25)	value
Age, year	33.41 ± 1.96	37.40 ± 1.92	0.167
Gender, M/F, n	2/15	3/22	1.000
BMI, kg/m^2	22.25 ± 0.86	25.74 ± 0.70	0.003
HR, beats/min	70.53 ± 2.34	66.71 ± 1.90	0.210
TG, mmol/L	0.73 (0.50, 0.91)	1.44 (1.05, 2.83)	≤ 0.001
TC, mmol/L	4.37 ± 0.21	6.25 ± 0.31	≤ 0.001
HDL-C, mmol/L	1.64 ± 0.09	1.68 ± 0.10	0.813
LDL-C, mmol/L	2.47 ± 0.22	3.46 ± 0.11	0.004
CK, U/L	84.00 (59.00, 105.00)	242.00 (144.50, 554.00)	≤ 0.001
FT3, pg/mL	2.80 ± 0.11	1.59 ± 0.10	≤ 0.001
FT4, ng/dL	1.12 (1.03, 1.16)	0.40 (0.40, 0.44)	≤ 0.001
TSH, mIU/mL	1.90 (1.44, 2.81)	100.00 (96.62, 100.00)	≤ 0.001
Irisin, ng/mL	59.96 ± 7.14	36.38 ± 5.61	0.014

Data are expressed as mean ± SME or median (interquartile range) unless stated otherwise. .